Palmitoyl-protein thioesterase 1
WebJun 2, 2003 · Mutations in palmitoyl protein thioesterase-1 (PPT1) have been found to cause the infantile form of neuronal ceroid lipofuscinosis, which is a lysosomal storage disorder characterized by impaired degradation of fatty acid-modified proteins with accumulation of amorphous granular deposits in cortical neurons, leading to mental … WebSynonyms: Palmitoyl-protein thioesterase 1(PPT-1), Palmitoyl-protein hydrolase 1 UniProt P50897 Pathways SARS-CoV-2 Protein Interactome; You are here: Homepage ELISA Kits PPT1 ELISA Kits PPT1 ELISA Kit (ABIN5593926) Service. Contact ...
Palmitoyl-protein thioesterase 1
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WebItem Recombinant Human Palmitoyl-Protein Thioesterase 1/PPT1 (C-6His) Company Bon Opus Biosciences; Price Pricing Info Supplier Page View Company Product Page; Catalog … WebPalmitoyl-protein thioesterase 1 removes certain fats called long-chain fatty acids from specific proteins, typically a fatty acid called palmitate. Removing these fatty acids helps break the proteins down when they are no longer needed. Palmitoyl-protein thioesterase 1 is also thought to be involved in a variety of other cell functions, such as
Web产品名称：PPT1 Antibody, Biotin conjugated产品货号：CSB-PA018587LD01HU产品别名：Ceroid palmitoyl palmitoyl protein thioesterase 1 antibody; CLN1 antibody; E WebMar 31, 2024 · Unbiased proteomics with acyl resin-assisted capture reveals diverse novel substrates of the depalmitoylating enzyme palmitoyl protein thioesterase 1 (PPT1) at the …
WebDec 20, 2005 · Palmitoyl-protein thioesterase-1 (PPT1), a lysosomal enzyme, cleaves thioester linkages in S-acylated proteins and removes palmitate residues facilitating the degradation of these proteins. Thus, inactivating mutations in the PPT1 gene cause infantile neuronal ceroid lipofuscinosis (INCL), a devastating neurodegenerative storage disorder … WebAlternative Names: Palmitoyl-protein thioesterase 1, PPT-1, EC 3.1.2.22, Palmitoyl-protein hydrolase 1, ppt-1 Mouse Anti-Arabidopsis PPT1 Antibody (CBMOAB-39266FYC) (CAT#: CBMOAB-39266FYC) Host species: Mouse
WebApr 18, 2000 · Mutations in palmitoyl-protein thioesterase 1 (PPT1), a lysosomal enzyme that removes fatty acyl groups from cysteine residues in modified proteins, cause the …
WebFunction. Acts as a acyl-protein thioesterase ( PubMed: 19439193, PubMed: 20418879 ). Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS ( PubMed: 20418879 ). Has depalmitoylating activity toward KCNMA1 ( PubMed: 22399288 ). Could also depalmitoylate ADRB2 ( PubMed: 27481942 ). golfer\u0027s dream golf clubWebMay 4, 2000 · Palmitoyl-protein thioesterase-1 (PPT1) is a newly described lysosomal enzyme that hydrolyzes long chain fatty acids from lipid-modified cysteine residues in proteins. Deficiency in this enzyme results in a severe neurodegenerative storage disorder, infantile neuronal ceroid lipofuscinosis. health advisory toxic smoke contaminantsWebPalmitoyl-protein thioesterase (PPT; EC 3.1.2.22) is a small glycoprotein that removes palmitate groups from cysteine residues in lipid-modified proteins.PPT is thought to be … golfer\u0027s elbow exercises arthritis ukWebJul 3, 2024 · 3.1 Palmitoyl protein thioesterase-1 was significantly increased in enzymatic activity in schizophrenia patients. Palmitoyl-protein thioesterase 1 was weakly correlated with functional magnetic resonance imaging in specific brain regions, 28 and the PPT1 gene was analysed as one of the candidate genes showing potential for a blood-based marker … golfer\u0027s elbow exercises handoutPalmitoyl protein hydrolase/thioesterases is an enzyme (EC 3.1.2.22) that removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation. It catalyzes the reaction palmitoyl[protein] + H2O palmitate + protein golfer\\u0027s elbow exercisesWebFig. 1 [35 S]Cysteine/methionine pulse-chase labeling of recombinant bovine palmitoyl-protein thioesterase in transiently transfected simian COS cells. Cells were transfected with plasmid pCMV-PPT, pulse-labeled for 15 min, and chased in the presence of unlabeled medium for varying periods of time as indicated. health advocacy groupWebPalmitoyl protein thioesterase 1 (PPT1) is a lysosomal hydrolase that catalyzes the cleavage of thioester linkages in palmitoylated peptides or proteins, which facilitates the degradation of these polypeptides (Camp and Hofmann, 1993; Zeidman et al., 2009). health advocacy benefit