Gm2a weight
WebFeb 8, 2024 · Table 2. Stem cell frequencies in GSCs (1517, 3565, and 3691) transduced with shCONT or shGM2A. GM2 ganglioside catabolism is critical to maintain GSC stemness. GM2A is a sphingolipid protein that presents GM2 gangliosides to the lysosomal β-hexosaminidase enzymes (HEXA and HEXB) for catabolism in lysosomes ( 48, 52 ). WebPredicted molecular weight. 19 kDa including tags. Amino acids. 26 to 193. Tags. His tag C-Terminus. Additional sequence information. This product is the full length protein from aa 26 to 193. The signal peptide is not included (NP_000396.2). ... Defects in GM2A are the cause of GM2-gangliosidosis type AB (GM2GAB) [MIM:272750]; also known as ...
Gm2a weight
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WebIMMUNOGEN: This GM2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-54 amino acids from the N-terminal region of human GM2A. CONJUGATE: Unconjugated; TESTED APPLICATIONS: WB; APPLICATION NOTE: For WB starting dilution is: 1:1000; PREDICTED MOLECULAR … WebOct 17, 2024 · Summary: The GM2A protein reduces neural firing and induces a loss of neurite integrity. Alzheimer’s disease (AD) currently has no cure and is predicted to affect …
WebTwo patients from Turkey with a novel variant in the GM2A gene and review of the literature. GM2-GM3 gangliosides ratio is dependent on GRP94 through down-regulation of GM2-AP cofactor in brain metastasis cells. Review of GM2A mutations causing GM2 activator protein deficiency and GM2 gangliosidosis-AB variant. Web康朗生物为您提供生物素蛋白连接酶抗体的参数及2024年最新报价，厂家专业的生物素蛋白连接酶抗体售后服务团队，是您值得 ...
WebOur GM2A polyclonal and monoclonal antibodies are developed in Rabbit, Mouse and Goat. These antibodies have been verified by Relative expression to confirm specificity to GM2A. Find the GM2A antibody that fits your needs. Choose from 1 of 14 GM2A antibodies, which have been validated in experiments with 2 publications and 34 images featured in ... WebSep 1, 2016 · A DNA fragment encoding GM2A with a histidine-tag (10xHis) and the signal sequence of human lysosomal α-galactosidase A (GLA) was ligated into the pCXN 2 ... (w/v) acrylamide gel and silver staining with a Dodeca Silver Stain Kit (Bio-Rad). The molecular weight of GM2A was calculated based on those of the APRO markers (APRO Science, …
WebJul 6, 2016 · The GM2 activator is a low molecular weight, soluble protein that binds to the GM2 ganglioside, extracts it from the membrane, and solubilizes it as an activator/lipid …
WebNational Center for Biotechnology Information outsource synonymWebGM2-gangliosidosis, AB variant is a rare inherited disorder that progressively destroys nerve cells (neurons) in the brain and spinal cord. Signs and symptoms of the AB variant … outsource technologyWebAug 25, 2024 · Establishing the Diagnosis. The diagnosis of GM2 activator deficiency is established in a proband with suggestive findings, normal beta-hexosaminidase A (HEX A) enzyme activity levels, and biallelic … outsource texasWebGM2-gangliosidosis, AB variant is a rare inherited disorder that progressively destroys nerve cells (neurons) in the brain and spinal cord. Signs and symptoms of the AB variant become apparent in infancy. Infants with this disorder typically appear normal until the age of 3 to 6 months, when their development slows and muscles used for movement ... outsource unclaimed propertyWebThe GM2A gene provides instructions for making a protein called the ganglioside GM2 activator. This protein is necessary for the normal function of an enzyme called beta-hexosaminidase A, which plays a critical role in the brain and spinal cord (central nervous system). Beta-hexosaminidase A and the ganglioside GM2 activator protein work ... raised grain brewing co. waukeshaWebThe GM2A gene provides instructions for making a protein called the ganglioside GM2 activator. This protein is necessary for the normal function of an enzyme called beta … outsource trackingWebMolecular Weight: 164.16. Compare Product No. Description SDS Pricing; ... Hide. Match Criteria: Keyword, Product Name. GM2A. GM2 ganglioside activator. Synonyms: GM2 … raised grain vinyl flooring maintenance